2,3-Dichloro-5,6-dicyano-p-benzoquinone (DDQ)

CAS NO. 84-58-2


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Benzoquinone Aromatic carbonyl Quinone Derivatives Oxidizing Agents pharmaceutical intermediate Nitrile Compounds

Product Description

Applications

Parameter	Standard Specification
Product Name	2,3-Dichloro-5,6-dicyano-p-benzoquinone (DDQ)
CAS Number	84-58-2
Molecular Formula	C₈Cl₂N₂O₂
Appearance	Yellow crystalline powder
Identification	Complies with standard
Solubility	Soluble in methanol and acetone
Melting Point	213-218°C
Loss on Drying	≤ 0.5%
Assay (HPLC)	98.0% - 100.0%
Residual Solvents (Benzene)	≤ 350 ppm
Flash Point	112°C (closed cup)
Storage Conditions	Store in tight, light-resistant containers at controlled room temperature

✓ All test results comply with enterprise standard requirements. Product manufactured under GMP conditions with full quality assurance.

Industrial Applications of DDQ (CAS 84-58-2)

DDQ is an oxidizing and dehydrogenating agent essential for complex organic synthesis. Widely used across pharmaceutical, fine chemical, and biotechnology industries, DDQ enables selective transformations that are difficult to achieve with conventional reagents, making it indispensable for high-value API manufacturing and advanced chemical processes.

• Pharmaceutical Manufacturing

Critical reagent for steroid synthesis and API production. DDQ enables selective dehydrogenation of testosterone derivatives, aromatization reactions, and complex molecular modifications essential for drug manufacturing.

Productos finales: Rosuvastatin, steroid hormones, equilin, corticosteroids, anti-HIV drugs (Efavirenz)

• Fine Chemical Synthesis

Versatile oxidant for custom synthesis projects, enabling selective alcohol oxidation, deprotection of protecting groups (PMB, benzyl ethers), and oxidative cyclization reactions under mild conditions.

Productos finales: α,β-unsaturated compounds, quinolines, benzisoxazoles, pharmaceutical intermediates

• Biotechnology & Life Sciences

DDQ-1 derivatives serve as non-fluorescent quenchers in oligonucleotide synthesis for molecular diagnostics, real-time PCR applications, and therapeutic oligonucleotide development.

Productos finales: DNA/RNA probes, diagnostic assays, molecular biology reagents

• Analytical Chemistry

Analytical reagent for pharmaceutical quality control through charge-transfer complex formation, enabling spectrophotometric determination of active ingredients in drug formulations.

Productos finales: Quality control methods for Ceritinib, Lorlatinib, Caroverine analysis

Key Advantage: DDQ's reduction potential and selectivity enable transformations impossible with conventional oxidants, making it essential for complex synthesis.

Product Description

Applications

2,3-Dichloro-5,6-dicyano-p-benzoquinone (DDQ)

Industrial Applications of DDQ (CAS 84-58-2)

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